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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM50034777'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM50034777
PNG
(CHEMBL3360973)
Show SMILES CC(C)(O)c1cn(c(Cc2ccccc2C(F)(F)F)n1)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O
Show InChI InChI=1S/C27H25F3N2O3S/c1-26(2,33)24-17-32(25(31-24)16-20-7-4-5-10-23(20)27(28,29)30)21-13-11-18(12-14-21)19-8-6-9-22(15-19)36(3,34)35/h4-15,17,33H,16H2,1-3H3
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Article
PubMed
n/an/an/an/a 200n/an/an/an/a



Bristol-Myers Squibb

Curated by ChEMBL


Assay Description
Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay

Bioorg Med Chem Lett 25: 372-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.11.029
BindingDB Entry DOI: 10.7270/Q2154JN9
More data for this
Ligand-Target Pair