BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha' and Ligand = 'BDBM50172199'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))
BDBM50172199
PNG
(1-Phenyl-cyclohexanecarboxylic acid ((1S,4aS,10aR)...)
Show SMILES C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NC(=O)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C30H37NO2/c1-28-18-11-19-29(2,25(28)17-16-22-12-7-8-15-24(22)28)26(32)31-27(33)30(20-9-4-10-21-30)23-13-5-3-6-14-23/h3,5-8,12-15,25H,4,9-11,16-21H2,1-2H3,(H,31,32,33)/t25-,28-,29+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 420n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibitory concentration in LXRSPA alpha binding assay


Bioorg Med Chem Lett 15: 4574-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.100
BindingDB Entry DOI: 10.7270/Q2154GKK
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))
BDBM50172199
PNG
(1-Phenyl-cyclohexanecarboxylic acid ((1S,4aS,10aR)...)
Show SMILES C[C@@]1(CCC[C@@]2(C)[C@H]1CCc1ccccc21)C(=O)NC(=O)C1(CCCCC1)c1ccccc1
Show InChI InChI=1S/C30H37NO2/c1-28-18-11-19-29(2,25(28)17-16-22-12-7-8-15-24(22)28)26(32)31-27(33)30(20-9-4-10-21-30)23-13-5-3-6-14-23/h3,5-8,12-15,25H,4,9-11,16-21H2,1-2H3,(H,31,32,33)/t25-,28-,29+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 170n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Effective concentration in recombinant human LXRalpha ligand binding domain in homogeneous time-resolved fluorescence assay


Bioorg Med Chem Lett 15: 4574-8 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.100
BindingDB Entry DOI: 10.7270/Q2154GKK
More data for this
Ligand-Target Pair