BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Oxysterols receptor LXR-alpha [197-447]' and Ligand = 'BDBM35087'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35087 (BMC171663 Compound 4a \| Benzylquinoline, 8a) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
Wyeth Research					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35087 (BMC171663 Compound 4a \| Benzylquinoline, 8a) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXRalpha coated flash plates. Each concentration of...				Bioorg Med Chem 17: 8086-92 (2009) Article DOI: 10.1016/j.bmc.2009.10.001 BindingDB Entry DOI: 10.7270/Q2VH5M54
Wyeth Research					More data for this Ligand-Target Pair