Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM241743'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241743 (US9409917, 40) Show SMILES FC(F)(F)c1cccc(CNC(=O)C2CCOc3ncccc23)c1Cl Show InChI InChI=1S/C17H14ClF3N2O2/c18-14-10(3-1-5-13(14)17(19,20)21)9-23-15(24)11-6-8-25-16-12(11)4-2-7-22-16/h1-5,7,11H,6,8-9H2,(H,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
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