Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM241814'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241814 (US9409917, 111 | US9409917, 112) Show SMILES Clc1cccc2CCC[C@@H](NC(=O)C3COc4ncccc34)c12 Show InChI InChI=1S/C18H17ClN2O2/c19-14-7-1-4-11-5-2-8-15(16(11)14)21-17(22)13-10-23-18-12(13)6-3-9-20-18/h1,3-4,6-7,9,13,15H,2,5,8,10H2,(H,21,22)/t13?,15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM241814 (US9409917, 111 | US9409917, 112) Show SMILES Clc1cccc2CCC[C@@H](NC(=O)C3COc4ncccc34)c12 Show InChI InChI=1S/C18H17ClN2O2/c19-14-7-1-4-11-5-2-8-15(16(11)14)21-17(22)13-10-23-18-12(13)6-3-9-20-18/h1,3-4,6-7,9,13,15H,2,5,8,10H2,(H,21,22)/t13?,15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	37
ACTELION PHARMACEUTICALS LTD. US Patent					Assay Description HEK cells stably expressing P2X7 were used to screen drugs using the YO-PRO1 assay. Cells were grown to confluency in adherent culture at 37° C. ...				US Patent US9409917 (2016) BindingDB Entry DOI: 10.7270/Q2ZS2VC8
					More data for this Ligand-Target Pair