Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50110106'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50110106 (CHEMBL3604421) Show SMILES C[C@H]1Cn2c(CN1C(=O)c1cccc(c1Cl)C(F)(F)F)nnc2-c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H15ClF4N4O/c1-11-9-29-16(26-27-18(29)12-5-7-13(22)8-6-12)10-28(11)19(30)14-3-2-4-15(17(14)21)20(23,24)25/h2-8,11H,9-10H2,1H3/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as inhibition of BzATP-induced Ca2+ flux after 30 min...				Bioorg Med Chem Lett 25: 3157-63 (2015) Article DOI: 10.1016/j.bmcl.2015.06.004 BindingDB Entry DOI: 10.7270/Q2BV7JD0
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50110106 (CHEMBL3604421) Show SMILES C[C@H]1Cn2c(CN1C(=O)c1cccc(c1Cl)C(F)(F)F)nnc2-c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H15ClF4N4O/c1-11-9-29-16(26-27-18(29)12-5-7-13(22)8-6-12)10-28(11)19(30)14-3-2-4-15(17(14)21)20(23,24)25/h2-8,11H,9-10H2,1H3/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at rat P2X7 receptor assessed as inhibition of ATP-induced Ca2+ flux by FLIPR assay				Bioorg Med Chem Lett 25: 3157-63 (2015) Article DOI: 10.1016/j.bmcl.2015.06.004 BindingDB Entry DOI: 10.7270/Q2BV7JD0
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50110106 (CHEMBL3604421) Show SMILES C[C@H]1Cn2c(CN1C(=O)c1cccc(c1Cl)C(F)(F)F)nnc2-c1ccc(F)cc1 |r| Show InChI InChI=1S/C20H15ClF4N4O/c1-11-9-29-16(26-27-18(29)12-5-7-13(22)8-6-12)10-28(11)19(30)14-3-2-4-15(17(14)21)20(23,24)25/h2-8,11H,9-10H2,1H3/t11-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at P2X7 receptor in human whole blood assessed as inhibition of BzATP-induced IL1beta release incubated 30 mins prior to BzATP-ch...				Bioorg Med Chem Lett 25: 3157-63 (2015) Article DOI: 10.1016/j.bmcl.2015.06.004 BindingDB Entry DOI: 10.7270/Q2BV7JD0
					More data for this Ligand-Target Pair