Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50173582'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50173582 (CHEMBL3810255) Show SMILES COc1cccc(C(=O)N2Cc3nc(C)nc(-c4ccn[nH]4)c3CC2C)c1F Show InChI InChI=1S/C20H20FN5O2/c1-11-9-14-16(23-12(2)24-19(14)15-7-8-22-25-15)10-26(11)20(27)13-5-4-6-17(28-3)18(13)21/h4-8,11H,9-10H2,1-3H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Antagonist activity against human recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ fl...				ACS Med Chem Lett 7: 348-50 (2016) Article DOI: 10.1021/acsmedchemlett.6b00083 BindingDB Entry DOI: 10.7270/Q2CZ392F
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50173582 (CHEMBL3810255) Show SMILES COc1cccc(C(=O)N2Cc3nc(C)nc(-c4ccn[nH]4)c3CC2C)c1F Show InChI InChI=1S/C20H20FN5O2/c1-11-9-14-16(23-12(2)24-19(14)15-7-8-22-25-15)10-26(11)20(27)13-5-4-6-17(28-3)18(13)21/h4-8,11H,9-10H2,1-3H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Antagonist activity against rat recombinant ATP-gated P2X7 receptor expressed in human 1321N1 cells assessed as reduction in BzATP -induced Ca2+ flux...				ACS Med Chem Lett 7: 348-50 (2016) Article DOI: 10.1021/acsmedchemlett.6b00083 BindingDB Entry DOI: 10.7270/Q2CZ392F
					More data for this Ligand-Target Pair