Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 7' and Ligand = 'BDBM50416612'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50416612 (CHEMBL1222601) Show SMILES Fc1ccc(CNC(=O)[C@@H]2CCC(=O)N2c2ccccc2)c(Cl)c1 |r| Show InChI InChI=1S/C18H16ClFN2O2/c19-15-10-13(20)7-6-12(15)11-21-18(24)16-8-9-17(23)22(16)14-4-2-1-3-5-14/h1-7,10,16H,8-9,11H2,(H,21,24)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay				Bioorg Med Chem Lett 20: 5080-4 (2010) Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T
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