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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P2Y purinoceptor 14' and Ligand = 'BDBM50343110'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P2Y purinoceptor 14


(Mus musculus)		BDBM50343110
PNG
(CHEMBL1771245 | N-(3-(1,1-difluoroethyl)phenyl)-2-...)
Show SMILES Cc1ccccc1-c1nc(nc2CCN(Cc12)C(=O)Nc1cccc(c1)C(C)(F)F)-c1cccnc1
Show InChI InChI=1S/C28H25F2N5O/c1-18-7-3-4-11-22(18)25-23-17-35(27(36)32-21-10-5-9-20(15-21)28(2,29)30)14-12-24(23)33-26(34-25)19-8-6-13-31-16-19/h3-11,13,15-16H,12,14,17H2,1-2H3,(H,32,36)
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Merck Frosst Center for Therapeutic Research

Curated by ChEMBL


Assay Description
Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...

Bioorg Med Chem Lett 21: 2832-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.03.084
BindingDB Entry DOI: 10.7270/Q20865N7
More data for this
Ligand-Target Pair