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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534]' and Ligand = 'BDBM525649'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
P61964[22-334]/Q03164[3745-3969]/Q15291/Q9C005/Q9UBL3[2-534]


(Human-Homo sapiens (Human))		BDBM525649
PNG
(US11174250, Example 67)
Show SMILES CN(Cc1ccc(F)c(c1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c1)C1CCCCC1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.15E+3n/an/an/an/an/an/a


TBA

Assay Description
Compound potency was assessed through incorporation of 3H-SAM into oligonucleosomes purified from HeLa cells. Specifically, recombinant human MLL1 (a...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2C53Q0K
More data for this
Ligand-Target Pair