Found 8 hits Enz. Inhib. hit(s) with Target = 'Penicillin-binding protein 2x' and Ligand = 'BDBM50213266' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 60.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 334 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 597 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 634 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50213266
(CHEBI:471744 | Imipenem | MK-0787)Show SMILES [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
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