Found 8 hits Enz. Inhib. hit(s) with Target = 'Penicillin-binding protein 2x' and Ligand = 'BDBM50483324' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 59.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3676 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 2527 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 136 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3243 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 213 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3009 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 1076 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 606 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3665 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 686 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 1077 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
Penicillin-binding protein 2x
(Streptococcus pneumoniae) | BDBM50483324
(CHEBI:51257 | Faropenem)Show SMILES [H][C@]12SC(=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O)[C@@]1([H])CCCO1 |c:3| Show InChI InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hershey Medical Center
Curated by ChEMBL
| Assay Description
Displacement of Biocillin FL from Streptococcus pneumoniae 3413 PBP2X |
Antimicrob Agents Chemother 53: 2176-80 (2009)
Article DOI: 10.1128/AAC.01566-08
BindingDB Entry DOI: 10.7270/Q24B345B |
More data for this
Ligand-Target Pair | |
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