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Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase A' and Ligand = 'BDBM50125721'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase A


(Rattus norvegicus)		BDBM50125721
PNG
(3,5-Dichloro-N-[3-(2-naphthalen-1-yl-acetylamino)-...)
Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1cccc(NC(=O)Cc2cccc3ccccc23)c1
Show InChI InChI=1S/C25H18Cl2N2O2/c26-19-11-18(12-20(27)14-19)25(31)29-22-9-4-8-21(15-22)28-24(30)13-17-7-3-6-16-5-1-2-10-23(16)17/h1-12,14-15H,13H2,(H,28,30)(H,29,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.12E+3n/an/an/an/an/an/a



Guilford Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)

J Med Chem 46: 1112-5 (2003)


Article DOI: 10.1021/jm020409u
BindingDB Entry DOI: 10.7270/Q2V1244X
More data for this
Ligand-Target Pair