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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase A' and Ligand = 'BDBM50125723'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase A


(Rattus norvegicus)		BDBM50125723
PNG
(1-(2,4-Dibromo-phenyl)-3-{3-[3-(2,4-dibromo-phenyl...)
Show SMILES Brc1ccc(NC(=O)NC2CCCC(C2)NC(=O)Nc2ccc(Br)cc2Br)c(Br)c1
Show InChI InChI=1S/C20H20Br4N4O2/c21-11-4-6-17(15(23)8-11)27-19(29)25-13-2-1-3-14(10-13)26-20(30)28-18-7-5-12(22)9-16(18)24/h4-9,13-14H,1-3,10H2,(H2,25,27,29)(H2,26,28,30)
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KEGG

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PC cid
PC sid
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Patents
Article
PubMed
n/an/a 5.09E+3n/an/an/an/an/an/a



Guilford Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)

J Med Chem 46: 1112-5 (2003)


Article DOI: 10.1021/jm020409u
BindingDB Entry DOI: 10.7270/Q2V1244X
More data for this
Ligand-Target Pair