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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase A' and Ligand = 'BDBM50125728'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase A


(Rattus norvegicus)		BDBM50125728
PNG
(CHEMBL13550 | N-(3,5-dichlorophenyl)-N'-{3-[({[(3,...)
Show SMILES Clc1cc(Cl)cc(NC(=O)NCc2cccc(CNC(=O)Nc3cc(Cl)cc(Cl)c3)c2)c1
Show InChI InChI=1S/C22H18Cl4N4O2/c23-15-5-16(24)8-19(7-15)29-21(31)27-11-13-2-1-3-14(4-13)12-28-22(32)30-20-9-17(25)6-18(26)10-20/h1-10H,11-12H2,(H2,27,29,31)(H2,28,30,32)
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 3.95E+3n/an/an/an/an/an/a



Guilford Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)

J Med Chem 46: 1112-5 (2003)


Article DOI: 10.1021/jm020409u
BindingDB Entry DOI: 10.7270/Q2V1244X
More data for this
Ligand-Target Pair