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Found 1 hit Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase A' and Ligand = 'BDBM50125729'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peptidyl-prolyl cis-trans isomerase A


(Rattus norvegicus)		BDBM50125729
PNG
(3,5-Dichloro-N-{3-[3-(2,4-dibromo-phenyl)-ureido]-...)
Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1cccc(NC(=O)Nc2ccc(Br)cc2Br)c1
Show InChI InChI=1S/C20H13Br2Cl2N3O2/c21-12-4-5-18(17(22)8-12)27-20(29)26-16-3-1-2-15(10-16)25-19(28)11-6-13(23)9-14(24)7-11/h1-10H,(H,25,28)(H2,26,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Guilford Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)

J Med Chem 46: 1112-5 (2003)


Article DOI: 10.1021/jm020409u
BindingDB Entry DOI: 10.7270/Q2V1244X
More data for this
Ligand-Target Pair