Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Perforin-1' and Ligand = 'BDBM50361424'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Perforin-1 (Homo sapiens (Human))	BDBM50361424 (CHEMBL1934388) Show SMILES O=C1OCc2cc(ccc12)-c1cccs1 Show InChI InChI=1S/C12H8O2S/c13-12-10-4-3-8(6-9(10)7-14-12)11-2-1-5-15-11/h1-6H,7H2	NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incub...				Bioorg Med Chem 20: 1319-36 (2012) Article DOI: 10.1016/j.bmc.2011.12.011 BindingDB Entry DOI: 10.7270/Q29C6XW9
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