BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Peroxisomal membrane protein PEX14' and Ligand = 'BDBM50520198'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisomal membrane protein PEX14


(Homo sapiens (Human))		BDBM50520198
PNG
(CHEMBL4439649)
Show SMILES COc1ccc(CN2CCc3c(C2)c(nn3CCO)C(=O)NCc2cccc3ccccc23)cc1OC
Show InChI InChI=1S/C29H32N4O4/c1-36-26-11-10-20(16-27(26)37-2)18-32-13-12-25-24(19-32)28(31-33(25)14-15-34)29(35)30-17-22-8-5-7-21-6-3-4-9-23(21)22/h3-11,16,34H,12-15,17-19H2,1-2H3,(H,30,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.38E+5n/an/an/an/a



Technische Universit£t M£nchen

Curated by ChEMBL


Assay Description
Inhibition of biotinylated PEX5-derived ALSENWAQEFLA binding to human N-terminal His-tagged PEX14 (21 to 84 residues) expressed in Escherichia coli B...

J Med Chem 63: 847-879 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01876
BindingDB Entry DOI: 10.7270/Q20G3PJ1
More data for this
Ligand-Target Pair