BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha' and Ligand = 'BDBM50309072'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50309072 (CHEMBL592054 \| IMIGLITAZAR) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha transactivation expressed in human HePG2 cells				Bioorg Med Chem Lett 18: 6471-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.062 BindingDB Entry DOI: 10.7270/Q2BK1D9Z
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50309072 (CHEMBL592054 \| IMIGLITAZAR) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Agonist activity at human full length PPARalpha expressed in human HepG2 cells cotransfected with PPRE3-TK-luc assessed as induction of beta-galactos...				Bioorg Med Chem Lett 20: 1156-61 (2010) Article DOI: 10.1016/j.bmcl.2009.12.022 BindingDB Entry DOI: 10.7270/Q20865FJ
Zydus Research Centre Curated by ChEMBL					More data for this Ligand-Target Pair