Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor delta' and Ligand = 'BDBM50192837'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50192837 (CHEMBL3964816 | US10188627, Compound 8d) Show SMILES CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(-c2ccco2)c(Cl)c1 Show InChI InChI=1S/C26H26ClNO5/c1-18(9-12-25(29)30)13-15-33-23-7-4-3-6-20(23)17-28(2)26(31)19-10-11-21(22(27)16-19)24-8-5-14-32-24/h3-8,10-11,13-14,16H,9,12,15,17H2,1-2H3,(H,29,30)/b18-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Temple University Curated by ChEMBL					Assay Description Transactivation of ProLink tagged human PPARdelta transfected in CHO-K1 cells assessed as interaction with EA labelled SRCP after 3 to 16 hrs by beta...				ACS Med Chem Lett 7: 824-5 (2016) Article DOI: 10.1021/acsmedchemlett.6b00301 BindingDB Entry DOI: 10.7270/Q2WH2RZ8
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50192837 (CHEMBL3964816 | US10188627, Compound 8d) Show SMILES CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(-c2ccco2)c(Cl)c1 Show InChI InChI=1S/C26H26ClNO5/c1-18(9-12-25(29)30)13-15-33-23-7-4-3-6-20(23)17-28(2)26(31)19-10-11-21(22(27)16-19)24-8-5-14-32-24/h3-8,10-11,13-14,16H,9,12,15,17H2,1-2H3,(H,29,30)/b18-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Mitobridge, Inc.; Salk Institute for Biological Studies US Patent					Assay Description Cell Handling: PathHunter NHR cell lines were expanded from freezer stocks according to standard procedures. Cells were seeded in a total volume of 2...				US Patent US10188627 (2019) BindingDB Entry DOI: 10.7270/Q2HX1FR6
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50192837 (CHEMBL3964816 | US10188627, Compound 8d) Show SMILES CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(-c2ccco2)c(Cl)c1 Show InChI InChI=1S/C26H26ClNO5/c1-18(9-12-25(29)30)13-15-33-23-7-4-3-6-20(23)17-28(2)26(31)19-10-11-21(22(27)16-19)24-8-5-14-32-24/h3-8,10-11,13-14,16H,9,12,15,17H2,1-2H3,(H,29,30)/b18-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.59	n/a	n/a	n/a	n/a
Mitobridge, Inc.; Salk Institute for Biological Studies US Patent					Assay Description Medium including test compound was aspirated and washed with PBS. 50 μl PBS including 1 mM Mg++ and Ca++ were then added to each well. The lucif...				US Patent US10188627 (2019) BindingDB Entry DOI: 10.7270/Q2HX1FR6
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50192837 (CHEMBL3964816 | US10188627, Compound 8d) Show SMILES CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc(-c2ccco2)c(Cl)c1 Show InChI InChI=1S/C26H26ClNO5/c1-18(9-12-25(29)30)13-15-33-23-7-4-3-6-20(23)17-28(2)26(31)19-10-11-21(22(27)16-19)24-8-5-14-32-24/h3-8,10-11,13-14,16H,9,12,15,17H2,1-2H3,(H,29,30)/b18-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.40	n/a	n/a	n/a	n/a
Temple University Curated by ChEMBL					Assay Description Transactivation of human Gal4-PPARdelta LBD transfected in African green monkey CV1 cells after 24 hrs by luciferase reporter gene assay				ACS Med Chem Lett 7: 824-5 (2016) Article DOI: 10.1021/acsmedchemlett.6b00301 BindingDB Entry DOI: 10.7270/Q2WH2RZ8
					More data for this Ligand-Target Pair