BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform' and Ligand = 'BDBM50193013'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50193013 (Duvelisib \| INK-1147 \| INK-1197 \| IPI-145) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Hutchison MediPharma Limited Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged recombinant full length human p110beta/untagged recombinant full length human p85alpha expressed in baculovirus ...				J Med Chem 62: 4936-4948 (2019) Article DOI: 10.1021/acs.jmedchem.8b02014 BindingDB Entry DOI: 10.7270/Q20R9SR0
Hutchison MediPharma Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50193013 (Duvelisib \| INK-1147 \| INK-1197 \| IPI-145) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					Assay Description Inhibition of PI3KCbeta/PIK3R1 (unknown origin)				Eur J Med Chem 158: 405-413 (2018) Article DOI: 10.1016/j.ejmech.2018.09.033 BindingDB Entry DOI: 10.7270/Q2KS6V81
INSERM 1052/CNRS 5286/University of Lyon Curated by ChEMBL					More data for this Ligand-Target Pair