Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM259452'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM259452 (US9512114, 12 | US9657007, Example 12) Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnn(C)n1)c1cc2cccc(Cl)c2c(=O)n1C1CC1 |r| Show InChI InChI=1S/C20H20ClN9O/c1-10(25-18-16(17(22)23-9-24-18)19-26-28-29(2)27-19)14-8-11-4-3-5-13(21)15(11)20(31)30(14)12-6-7-12/h3-5,8-10,12H,6-7H2,1-2H3,(H3,22,23,24,25)/t10-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as...				US Patent US9512114 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PWS
					More data for this Ligand-Target Pair