Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM259454'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM259454 (US9512114, 18 | US9657007, Example 18) Show SMILES CC[C@H](Nc1ncnc(N)c1-c1noc(C)n1)c1cc2cccc(F)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C25H22FN7O2/c1-3-18(31-23-21(22(27)28-13-29-23)24-30-14(2)35-32-24)19-12-15-8-7-11-17(26)20(15)25(34)33(19)16-9-5-4-6-10-16/h4-13,18H,3H2,1-2H3,(H3,27,28,29,31)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	25
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD. US Patent					Assay Description PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as...				US Patent US9512114 (2016) BindingDB Entry DOI: 10.7270/Q2TT4PWS
					More data for this Ligand-Target Pair