Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50575903'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50575903 (CHEMBL4858121) Show SMILES CCn1c(nc2c(N[C@H]3CCN(C3)C(=O)[C@@H]3C[C@@H](C3)OC)ncnc12)-c1cnc(C)nc1 |r,wU:15.15,17.20,wD:8.7,(5.22,-48.01,;6.72,-47.68,;7.19,-46.21,;6.28,-44.98,;7.17,-43.73,;8.63,-44.19,;9.97,-43.42,;9.96,-41.88,;11.29,-41.1,;12.7,-41.71,;13.72,-40.56,;12.94,-39.23,;11.44,-39.56,;13.56,-37.82,;12.65,-36.58,;15.09,-37.66,;16.29,-38.62,;17.25,-37.42,;16.05,-36.46,;18.78,-37.25,;19.7,-38.49,;11.3,-44.17,;11.32,-45.71,;9.98,-46.49,;8.64,-45.73,;4.74,-44.99,;3.96,-43.66,;2.5,-43.58,;1.66,-45.01,;.12,-45.02,;2.45,-46.34,;3.99,-46.32,)| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00237 BindingDB Entry DOI: 10.7270/Q28919NT
					More data for this Ligand-Target Pair