Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 3-kinase regulatory subunit beta' and Ligand = 'BDBM320519'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit beta (Homo sapiens (Human))	BDBM320519 (US10174035, Compound 65 | {4-[cis-2,6-Dimethylmorp...) Show SMILES C[C@H]1CN(C[C@@H](C)O1)C1CCN(CC1)C(=O)c1nc2c(nc(nc2[nH]1)-c1cn[nH]c1)N1CCOCC1 Show InChI InChI=1S/C24H33N9O3/c1-15-13-33(14-16(2)36-15)18-3-5-32(6-4-18)24(34)22-27-19-21(29-22)28-20(17-11-25-26-12-17)30-23(19)31-7-9-35-10-8-31/h11-12,15-16,18H,3-10,13-14H2,1-2H3,(H,25,26)(H,27,28,29,30)/t15-,16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
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