Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM132089'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM132089 (US8841288, TP714) Show SMILES Oc1ccccc1-n1cc(nn1)-c1cccc2c1[nH]c(cc2=O)N1CCOCC1 Show InChI InChI=1S/C21H19N5O3/c27-18-7-2-1-6-17(18)26-13-16(23-24-26)14-4-3-5-15-19(28)12-20(22-21(14)15)25-8-10-29-11-9-25/h1-7,12-13,27H,8-11H2,(H,22,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	25
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” US Patent					Assay Description Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-...				US Patent US8841288 (2014) BindingDB Entry DOI: 10.7270/Q2RJ4H5X
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