Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM132098 (US8841288, CL 129A) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | 25 |
Universtà Degli Studi di Torino; Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” US Patent | Assay Description Some compounds of formula (I) described herein were assayed in vitro for their ability to inhibit the lipid kinase activity of PI3Ks, by using a non-... | US Patent US8841288 (2014) BindingDB Entry DOI: 10.7270/Q2RJ4H5X | |||||||||||
More data for this Ligand-Target Pair |