Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50092780'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50092780 (CHEMBL3586385) Show SMILES O=C1CN(CCC2CCOCC2)c2nc(cnc2N1)-c1ccc(nc1)-c1nc[nH]n1 Show InChI InChI=1S/C20H22N8O2/c29-17-11-28(6-3-13-4-7-30-8-5-13)20-19(26-17)22-10-16(25-20)14-1-2-15(21-9-14)18-23-12-24-27-18/h1-2,9-10,12-13H,3-8,11H2,(H,22,26,29)(H,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of PI3K-alpha (unknown origin) by mobility shift assay				J Med Chem 58: 5323-33 (2015) Article DOI: 10.1021/acs.jmedchem.5b00626 BindingDB Entry DOI: 10.7270/Q208672F
					More data for this Ligand-Target Pair