Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50107320'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50107320 (CHEMBL3601174) Show SMILES Fc1ccccc1C(=O)OC(C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H15FO3/c22-18-14-8-7-13-17(18)21(24)25-20(16-11-5-2-6-12-16)19(23)15-9-3-1-4-10-15/h1-14,20H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah University of Jordan Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha H1047R mutant in human HCT116 cells assessed as cell growth inhibition after 24 hrs by MTT assay				Bioorg Med Chem Lett 25: 3120-4 (2015) Article DOI: 10.1016/j.bmcl.2015.06.011 BindingDB Entry DOI: 10.7270/Q2XW4MKJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50107320 (CHEMBL3601174) Show SMILES Fc1ccccc1C(=O)OC(C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H15FO3/c22-18-14-8-7-13-17(18)21(24)25-20(16-11-5-2-6-12-16)19(23)15-9-3-1-4-10-15/h1-14,20H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah University of Jordan Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha in human HCT116 cells assessed as cell growth inhibition after 24 hrs by MTT assay				Bioorg Med Chem Lett 25: 3120-4 (2015) Article DOI: 10.1016/j.bmcl.2015.06.011 BindingDB Entry DOI: 10.7270/Q2XW4MKJ
					More data for this Ligand-Target Pair