Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50243143'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50243143 (CHEMBL3109142) Show SMILES OCc1ccc(NC(=O)Nc2ccc(cc2)-c2nc(N3CCOCC3)c3ncccc3n2)cc1 Show InChI InChI=1S/C25H24N6O3/c32-16-17-3-7-19(8-4-17)27-25(33)28-20-9-5-18(6-10-20)23-29-21-2-1-11-26-22(21)24(30-23)31-12-14-34-15-13-31/h1-11,32H,12-16H2,(H2,27,28,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair