Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50425224'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50425224 (CHEMBL2314582) Show SMILES Oc1cccc(c1)-c1nc(nc2N(CCc12)c1nccs1)N1CCOCC1 Show InChI InChI=1S/C19H19N5O2S/c25-14-3-1-2-13(12-14)16-15-4-6-24(19-20-5-11-27-19)17(15)22-18(21-16)23-7-9-26-10-8-23/h1-3,5,11-12,25H,4,6-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) using phosphatidylinositol 4,5-bisphosphate as substrate				Bioorg Med Chem Lett 23: 673-8 (2013) Article DOI: 10.1016/j.bmcl.2012.11.112 BindingDB Entry DOI: 10.7270/Q2KS6SVT
					More data for this Ligand-Target Pair