Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50426813'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50426813 (CHEMBL2322778) Show SMILES NC(=O)c1ccc2-c3sc(cc3CCOc2c1)-c1ncnn1-c1ccc(F)cc1F Show InChI InChI=1S/C21H14F2N4O2S/c22-13-2-4-16(15(23)9-13)27-21(25-10-26-27)18-8-11-5-6-29-17-7-12(20(24)28)1-3-14(17)19(11)30-18/h1-4,7-10H,5-6H2,(H2,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha-mediated AKT Ser 473 phosphorylation in human PC3 cells				Bioorg Med Chem Lett 23: 897-901 (2013) Article DOI: 10.1016/j.bmcl.2012.10.121 BindingDB Entry DOI: 10.7270/Q21C1Z5X
					More data for this Ligand-Target Pair