Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50460055'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50460055 (CHEMBL4227858) Show SMILES CCC(=O)Nc1nc(C)c2cc(sc2n1)-c1cnc(OC)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C22H19F2N5O4S2/c1-4-19(30)27-22-26-11(2)14-9-17(34-21(14)28-22)12-7-16(20(33-3)25-10-12)29-35(31,32)18-6-5-13(23)8-15(18)24/h5-10,29H,4H2,1-3H3,(H,26,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate measured after 1 h...				Bioorg Med Chem 26: 637-646 (2018) Article DOI: 10.1016/j.bmc.2017.12.025 BindingDB Entry DOI: 10.7270/Q2JD50FF
					More data for this Ligand-Target Pair