Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM246891'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246891 (4-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimid...) Show SMILES COc1c(cc(Cl)c([N+]#[C-])c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H26ClN7O2/c1-11(31)7-29-8-14(9-29)18-19(25-4)16(23)6-15(20(18)32-5)13(3)30-22-17(12(2)28-30)21(24)26-10-27-22/h6,10-11,13-14,31H,7-9H2,1-3,5H3,(H2,24,26,27)/t11-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By ¿selective¿ is meant that the compound binds to or inhibits a kinase with greater affi...				US Patent US9708333 (2017) BindingDB Entry DOI: 10.7270/Q2KD20XW
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246891 (4-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimid...) Show SMILES COc1c(cc(Cl)c([N+]#[C-])c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H26ClN7O2/c1-11(31)7-29-8-14(9-29)18-19(25-4)16(23)6-15(20(18)32-5)13(3)30-22-17(12(2)28-30)21(24)26-10-27-22/h6,10-11,13-14,31H,7-9H2,1-3,5H3,(H2,24,26,27)/t11-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation US Patent					Assay Description In some embodiments, the PI3Kδ inhibitor is selective. By ¿selective¿ is meant that the compound binds to or inhibits a kinase with greater aff...				US Patent US10053465 (2018) BindingDB Entry DOI: 10.7270/Q2B27X98
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM246891 (4-[1-(4-amino-3-methyl- 1H-pyrazolo[3,4- d]pyrimid...) Show SMILES COc1c(cc(Cl)c([N+]#[C-])c1C1CN(C[C@H](C)O)C1)C(C)n1nc(C)c2c(N)ncnc12 |r| Show InChI InChI=1S/C22H26ClN7O2/c1-11(31)7-29-8-14(9-29)18-19(25-4)16(23)6-15(20(18)32-5)13(3)30-22-17(12(2)28-30)21(24)26-10-27-22/h6,10-11,13-14,31H,7-9H2,1-3,5H3,(H2,24,26,27)/t11-,13?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	6.7	25
Incyte Corporation US Patent					Assay Description [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...				US Patent US10065963 (2018) BindingDB Entry DOI: 10.7270/Q2H41TFS
					More data for this Ligand-Target Pair