Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM320578'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM320578 (N-methyl-5-(1-methyl-1H-pyrazol-4-yl)-7-(morpholin...) Show SMILES CN(C1CCN(CC1)C1CCOCC1)C(=O)c1nc2c(cc(nc2[nH]1)-c1cnn(C)c1)N1CCOCC1 Show InChI InChI=1S/C26H36N8O3/c1-31-17-18(16-27-31)21-15-22(34-9-13-37-14-10-34)23-24(28-21)30-25(29-23)26(35)32(2)19-3-7-33(8-4-19)20-5-11-36-12-6-20/h15-17,19-20H,3-14H2,1-2H3,(H,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
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