Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM489256'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM489256 (6-(4-Methyl-2-{[6-(2-oxo-1,3-oxazinan-3-yl)pyridin...) Show SMILES CC(C)NS(=O)(=O)c1cc(cc2CN([C@@H](C)C(F)(F)F)C(=O)c12)-c1sc(Nc2cccc(n2)N2CCCOC2=O)nc1C |r| Show InChI InChI=1S/C27H29F3N6O5S2/c1-14(2)34-43(39,40)19-12-17(11-18-13-36(24(37)22(18)19)16(4)27(28,29)30)23-15(3)31-25(42-23)33-20-7-5-8-21(32-20)35-9-6-10-41-26(35)38/h5,7-8,11-12,14,16,34H,6,9-10,13H2,1-4H3,(H,31,32,33)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...				US Patent US10961236 (2021) BindingDB Entry DOI: 10.7270/Q2M90CS5
					More data for this Ligand-Target Pair