Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM489269'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM489269 (2-[(1S)-1-Cyclopropylethyl]-N-methyl-6-[4-methyl-2...) Show SMILES CNS(=O)(=O)c1cc(cc2CN([C@@H](C)C3CC3)C(=O)c12)-c1sc(Nc2cccc(n2)N2C[C@H](C)NCC2=O)nc1C |r| Show InChI InChI=1S/C28H33N7O4S2/c1-15-13-35(24(36)12-30-15)23-7-5-6-22(32-23)33-28-31-16(2)26(40-28)19-10-20-14-34(17(3)18-8-9-18)27(37)25(20)21(11-19)41(38,39)29-4/h5-7,10-11,15,17-18,29-30H,8-9,12-14H2,1-4H3,(H,31,32,33)/t15-,17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...				US Patent US10961236 (2021) BindingDB Entry DOI: 10.7270/Q2M90CS5
					More data for this Ligand-Target Pair