Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM489284'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM489284 (2-[(1S)-1-Cyclopropylethyl]-6-[2-({6-[(2S)-2-(hydr...) Show SMILES CNS(=O)(=O)c1cc(cc2CN([C@@H](C)C3CC3)C(=O)c12)-c1sc(Nc2cccc(n2)N2[C@H](CO)CCC2=O)nc1C |r| Show InChI InChI=1S/C28H32N6O5S2/c1-15-26(40-28(30-15)32-22-5-4-6-23(31-22)34-20(14-35)9-10-24(34)36)18-11-19-13-33(16(2)17-7-8-17)27(37)25(19)21(12-18)41(38,39)29-3/h4-6,11-12,16-17,20,29,35H,7-10,13-14H2,1-3H3,(H,30,31,32)/t16-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The activity of recombinant human PI3Kγ ((aa144-1102)-6His) and PI3Kα, β, δ (6-His(p110-p85α)) was determined by measuring t...				US Patent US10961236 (2021) BindingDB Entry DOI: 10.7270/Q2M90CS5
					More data for this Ligand-Target Pair