Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform' and Ligand = 'BDBM50387546'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50387546 (CHEMBL2057363) Show SMILES CN(C)C(=O)CNC(=O)Nc1nc2ccc(cn2n1)-c1cncc(c1)S(=O)(=O)NC(C)(C)C Show InChI InChI=1S/C20H26N8O4S/c1-20(2,3)26-33(31,32)15-8-14(9-21-10-15)13-6-7-16-23-18(25-28(16)12-13)24-19(30)22-11-17(29)27(4)5/h6-10,12,26H,11H2,1-5H3,(H2,22,24,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
Cellzome Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assay				Bioorg Med Chem Lett 22: 4546-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.121 BindingDB Entry DOI: 10.7270/Q2J38TMN
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