Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM320527'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM320527 (US10174035, Compound 72 | [6-(Morpholin-4-yl)-2-(1...) Show SMILES O=C(N1CCC2(COC2)CC1)c1nc2c(nc(nc2[nH]1)-c1cn[nH]c1)N1CCOCC1 Show InChI InChI=1S/C20H24N8O3/c29-19(28-3-1-20(2-4-28)11-31-12-20)17-23-14-16(25-17)24-15(13-9-21-22-10-13)26-18(14)27-5-7-30-8-6-27/h9-10H,1-8,11-12H2,(H,21,22)(H,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Company, Limited US Patent					Assay Description The Kinase-Glo luminescent kinase assay kit (from Promega) was used to measure kinase activity. In this assay, amount of ATP remaining in solution fo...				US Patent US10174035 (2019) BindingDB Entry DOI: 10.7270/Q2FB552Z
					More data for this Ligand-Target Pair