Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM50444446'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50444446 (CHEMBL3092367) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CC(F)(F)F)no1 Show InChI InChI=1S/C10H9F3N4O2S/c1-4-7(20-9(14-4)15-5(2)18)8-16-6(17-19-8)3-10(11,12)13/h3H2,1-2H3,(H,14,15,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATP				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Mus musculus (Mouse))	BDBM50444446 (CHEMBL3092367) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1nc(CC(F)(F)F)no1 Show InChI InChI=1S/C10H9F3N4O2S/c1-4-7(20-9(14-4)15-5(2)18)8-16-6(17-19-8)3-10(11,12)13/h3H2,1-2H3,(H,14,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	278	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma in mouse RAW264.7 cells assessed as C5a-mediated PKB/Akt phosphorylation preincubated for 30 mins followed by C5a stimulation...				Bioorg Med Chem 21: 7578-83 (2013) Article DOI: 10.1016/j.bmc.2013.10.042 BindingDB Entry DOI: 10.7270/Q27082W9
					More data for this Ligand-Target Pair