Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha' and Ligand = 'BDBM50527942'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (Homo sapiens)	BDBM50527942 (CHEMBL4458985) Show SMILES CC(=O)Nc1ccc(cc1)-c1cncc(\C=C2/SC(=N)NC2=O)c1 Show InChI InChI=1S/C17H14N4O2S/c1-10(22)20-14-4-2-12(3-5-14)13-6-11(8-19-9-13)7-15-16(23)21-17(18)24-15/h2-9H,1H3,(H,20,22)(H2,18,21,23)/b15-7-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay				J Med Chem 63: 4880-4895 (2020) Article DOI: 10.1021/acs.jmedchem.0c00227 BindingDB Entry DOI: 10.7270/Q2SB4964
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