Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 5-phosphate 4-kinase type-2 beta' and Ligand = 'BDBM50511419'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (Homo sapiens (Human))	BDBM50511419 (CHEMBL4517979) Show SMILES CN(C)C\C=C\C(=O)NC1CCC(CC1)C(=O)Nc1cccc(Nc2cc(ncn2)-c2cnc3[nH]ccc3c2)c1 |(4.78,-11.85,;6.12,-11.08,;6.12,-9.54,;7.45,-11.85,;8.78,-11.08,;10.12,-11.85,;11.45,-11.08,;11.45,-9.54,;12.78,-11.85,;14.11,-11.08,;15.44,-11.85,;16.78,-11.08,;16.78,-9.54,;15.44,-8.77,;14.11,-9.54,;18.11,-8.77,;18.11,-7.23,;19.44,-9.54,;20.77,-8.77,;20.77,-7.23,;22.11,-6.46,;23.44,-7.24,;23.44,-8.76,;24.78,-9.53,;26.11,-8.76,;27.45,-9.54,;28.78,-8.76,;28.78,-7.23,;27.44,-6.46,;26.11,-7.22,;30.11,-9.53,;30.11,-11.08,;31.44,-11.84,;32.77,-11.07,;34.24,-11.54,;35.14,-10.3,;34.24,-9.05,;32.77,-9.53,;31.44,-8.76,;22.12,-9.54,)| Show InChI InChI=1S/C30H34N8O2/c1-38(2)14-4-7-28(39)36-23-10-8-20(9-11-23)30(40)37-25-6-3-5-24(16-25)35-27-17-26(33-19-34-27)22-15-21-12-13-31-29(21)32-18-22/h3-7,12-13,15-20,23H,8-11,14H2,1-2H3,(H,31,32)(H,36,39)(H,37,40)(H,33,34,35)/b7-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of PI5P4Kbeta (unknown origin) incubated for 15 mins in presence of ATP by ADP-Glo assay				ACS Med Chem Lett 11: 346-352 (2020) Article DOI: 10.1021/acsmedchemlett.9b00402 BindingDB Entry DOI: 10.7270/Q2TM7FDP
					More data for this Ligand-Target Pair