Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Phospholipase D1' and Ligand = 'BDBM36416'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D1 (Homo sapiens (Human))	BDBM36416 (3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...) Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D1(PLD1).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36416 (3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...) Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D2(PLD2).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36416 (3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...) Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36416 (3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...) Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using human non-small-cell lung cancer cell line, Calu-1				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36416 (3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...) Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using HEK293-gfpPLD2 cell line				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair