Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Phospholipase D1' and Ligand = 'BDBM36424'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D1 (Homo sapiens (Human))	BDBM36424 (CID21428857 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccco1 Show InChI InChI=1S/C19H22N4O3/c24-18(17-6-3-13-26-17)20-9-12-22-10-7-14(8-11-22)23-16-5-2-1-4-15(16)21-19(23)25/h1-6,13-14H,7-12H2,(H,20,24)(H,21,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D1(PLD1).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36424 (CID21428857 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccco1 Show InChI InChI=1S/C19H22N4O3/c24-18(17-6-3-13-26-17)20-9-12-22-10-7-14(8-11-22)23-16-5-2-1-4-15(16)21-19(23)25/h1-6,13-14H,7-12H2,(H,20,24)(H,21,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36424 (CID21428857 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccco1 Show InChI InChI=1S/C19H22N4O3/c24-18(17-6-3-13-26-17)20-9-12-22-10-7-14(8-11-22)23-16-5-2-1-4-15(16)21-19(23)25/h1-6,13-14H,7-12H2,(H,20,24)(H,21,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	37
Vanderbilt University					Assay Description PLD in vitro enzymatic assay using phospholipase D2(PLD2).				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36424 (CID21428857 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccco1 Show InChI InChI=1S/C19H22N4O3/c24-18(17-6-3-13-26-17)20-9-12-22-10-7-14(8-11-22)23-16-5-2-1-4-15(16)21-19(23)25/h1-6,13-14H,7-12H2,(H,20,24)(H,21,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using HEK293-gfpPLD2 cell line				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair
Phospholipase D1 (Homo sapiens (Human))	BDBM36424 (CID21428857 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...) Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccco1 Show InChI InChI=1S/C19H22N4O3/c24-18(17-6-3-13-26-17)20-9-12-22-10-7-14(8-11-22)23-16-5-2-1-4-15(16)21-19(23)25/h1-6,13-14H,7-12H2,(H,20,24)(H,21,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	37
Vanderbilt University					Assay Description cell-based assay using human non-small-cell lung cancer cell line, Calu-1				Nat Chem Biol 5: 108-17 (2009) Article DOI: 10.1038/nchembio.140 BindingDB Entry DOI: 10.7270/Q2D50KBK
					More data for this Ligand-Target Pair