BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Plasmepsin IV [1-448]' and Ligand = 'BDBM50507801'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Plasmepsin IV [1-448]


(Plasmodium falciparum)		BDBM50507801
PNG
(CHEMBL4533511)
Show SMILES COc1cccc(c1)C(C)(C)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc(cc(c1)C(=O)NCC(C)(C)O)N1CCCCC1 |r|
Show InChI InChI=1S/C37H50N4O5/c1-36(2,45)25-38-34(43)27-20-28(22-30(21-27)41-17-10-7-11-18-41)35(44)40-32(19-26-13-8-6-9-14-26)33(42)24-39-37(3,4)29-15-12-16-31(23-29)46-5/h6,8-9,12-16,20-23,32-33,39,42,45H,7,10-11,17-19,24-25H2,1-5H3,(H,38,43)(H,40,44)/t32-,33+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Latvian Institute of Organic Synthesis

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...

Eur J Med Chem 163: 344-352 (2019)


Article DOI: 10.1016/j.ejmech.2018.11.068
BindingDB Entry DOI: 10.7270/Q2BV7KZK
More data for this
Ligand-Target Pair