Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Plasminogen [101-181]' and Ligand = 'BDBM290279'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290279 (10-Iodo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-2...) Show SMILES Ic1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C15H15IN4O/c16-10-2-1-3-11-14(10)15-18-13(21)8-12(20(15)19-11)9-4-6-17-7-5-9/h1-3,8-9,17H,4-7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290279 (10-Iodo-4-(piperidin-4-yl)pyrimido[1,2-b]indazol-2...) Show SMILES Ic1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C15H15IN4O/c16-10-2-1-3-11-14(10)15-18-13(21)8-12(20(15)19-11)9-4-6-17-7-5-9/h1-3,8-9,17H,4-7H2,(H,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair