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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Plasminogen [101-181]' and Ligand = 'BDBM290308'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Plasminogen [101-181]


(Homo sapiens (Human))
BDBM290308
PNG
((−)-trans-4-(2-Methylpiperidin-4-yl)-10-phen...)
Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(ccnc3nn12)-c1ccccc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/an/an/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...


US Patent US10668071 (2020)


BindingDB Entry DOI: 10.7270/Q2KP8554
More data for this
Ligand-Target Pair
Plasminogen [101-181]


(Homo sapiens (Human))
BDBM290308
PNG
((−)-trans-4-(2-Methylpiperidin-4-yl)-10-phen...)
Show SMILES CC1CC(CCN1)c1cc(=O)[nH]c2c3c(ccnc3nn12)-c1ccccc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/a7.0n/a



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...


US Patent US10098883 (2018)


BindingDB Entry DOI: 10.7270/Q2G73GSM
More data for this
Ligand-Target Pair