Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Plasminogen [101-181]' and Ligand = 'BDBM290333'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290333 (10-Isopropoxy-4-(piperidin-4-yl)pyrimido[1,2-b]ind...) Show SMILES CC(C)Oc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C18H22N4O2/c1-11(2)24-15-5-3-4-13-17(15)18-20-16(23)10-14(22(18)21-13)12-6-8-19-9-7-12/h3-5,10-12,19H,6-9H2,1-2H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...				US Patent US10668071 (2020) BindingDB Entry DOI: 10.7270/Q2KP8554
					More data for this Ligand-Target Pair
Plasminogen [101-181] (Homo sapiens (Human))	BDBM290333 (10-Isopropoxy-4-(piperidin-4-yl)pyrimido[1,2-b]ind...) Show SMILES CC(C)Oc1cccc2nn3c(cc(=O)[nH]c3c12)C1CCNCC1 Show InChI InChI=1S/C18H22N4O2/c1-11(2)24-15-5-3-4-13-17(15)18-20-16(23)10-14(22(18)21-13)12-6-8-19-9-7-12/h3-5,10-12,19H,6-9H2,1-2H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.0	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description The test compounds were dissolved in 1% acetic acid and further complemented with an equal volume of DMSO. The resulting stock solutions were seriall...				US Patent US10098883 (2018) BindingDB Entry DOI: 10.7270/Q2G73GSM
					More data for this Ligand-Target Pair