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Found 1 hit Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta' and Ligand = 'BDBM50039056'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor alpha/beta


(Homo sapiens (Human))
BDBM50039056
PNG
(Benzyl-(6,7-dimethoxy-quinolin-3-yl)-amine | CHEMB...)
Show SMILES COc1cc2cc(NCc3ccccc3)cnc2cc1OC
Show InChI InChI=1S/C18H18N2O2/c1-21-17-9-14-8-15(12-20-16(14)10-18(17)22-2)19-11-13-6-4-3-5-7-13/h3-10,12,19H,11H2,1-2H3
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n/an/a 80n/an/an/an/an/an/a



Rhône-Poulenc Rorer Central Research

Curated by ChEMBL


Assay Description
Inhibition of human PDGF receptor phosphorylation; 0.02-0.08


J Med Chem 37: 2129-37 (1994)


BindingDB Entry DOI: 10.7270/Q29Z93Z8
More data for this
Ligand-Target Pair